以jacalin为靶点的受体结合结构域聚糖作为治疗COVID-19的新方法免费

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In silico analysis revealed that a lectin, jacalin from jackfurit seeds recognize glycosylated region of receptor binding domain (RBD) of COVID-19. Jacalin binding induce conformational changes in RBD and significantly affect its interaction with human angiotensin-converting enzyme 2. The result may open up exploration of lectins based strategies against COVID-19.In silico analysis revealed that a lectin, jacalin from jackfurit seeds recognize glycosylated region of receptor binding domain (RBD) of COVID-19. Jacalin binding induce conformational changes in RBD and significantly affect its interaction with human angiotensin-converting enzyme 2. The result may open up exploration of lectins based strategies against COVID-19.