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**# # # Machine Learning Model for identifying Cell Nuclei from Histology Images** Machine learning model for identifying cell nuclei from histology images. The model having the ability to generalize across a variety of lighting conditions, cell types, magnifications, and imaging modalities.Imagine speeding up research for almost every disease, from lung cancer and heart disease to rare disorders. The Data Science Bowl offers to data scientist / practitioner a most ambitious mission i.e. create an algorithm to automate nucleus detection & create an algorithm to detect all non overlapped nuclei from the given test data i.e. It should have the capability for instance segmentation. We’ve all seen people suffer from diseases like cancer, heart disease, chronic obstructive pulmonary disease, Alzheimer’s, and diabetes. Many have seen their loved ones pass away. Think how many lives would be transformed if cures came faster. By automating nucleus detection, you could help unlock cures faster—from rare disorders to the common cold ***# ## Why nuclei?*** Identifying the cells’ nuclei is the starting point for most analyses because most of the human body’s 30 trillion cells contain a nucleus full of DNA, the genetic code that programs each cell. Identifying nuclei allows researchers to identify each individual cell in a sample, and by measuring how cells react to various treatments, the researcher can understand the underlying biological processes at work.By participating, teams will work to automate the process of identifying nuclei, which will allow for more efficient drug testing, shortening the 10 years it takes for each new drug to come to market Acknowledgements The success and final outcome of this project required a lot of guidance and assistance from many people and I am extremely privileged to have got this all along the completion of my project. All that I have done is only due to such supervision and assistance and I would not forget to thank them.I owe my deep gratitude to our project guide C - DAC Noida, who took keen interest on my project work and guided me all along, till the completion of our project work by providing all the necessary information for developing a good system. Inspiration The Data Science Bowl, presented by Booz Allen and Kaggle, is the world’s premier data science for social good competition. The Data Science Bowl brings together data scientists, technologists, domain experts, and organizations to take on the world’s challenges with data and technology. It’s a platform through which people can harness their passion, unleash their curiosity, and amplify their impact to effect change on a global scale